About Total Dermatology

Total Dermatology, located in Irvine and serving all of California, prides itself on providing the highest quality and most innovative technologies for various skin concerns. The practice is led by Dr. Nissan Pilest, a board-certified dermatologist with a national reputation and over 40 years of experience in treating medical and cosmetic patients. Patients have reported having positive experiences at Total Dermatology, with one patient sharing that they have been going to the practice for over a decade and that Dr. Pilest was the only one to successfully treat their acne. The office is noted for its friendly and helpful staff and nurses. Patients describe the doctor as sweet, knowledgeable, and an expert in his field. Reviewers praise Dr. Pilest as a "Skin Wizard" with an immaculate office and wonderful staff. They highlight his expertise in handling various skin issues and medical procedures, resulting in minimal to no scarring. Patients recommend visiting Total Dermatology for all their skin needs, emphasizing Dr. Pilest's kind and funny demeanor, as well as the reasonableness of the practice's prices.

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Reviews for Total Dermatology

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  • Feb 2026

    Hello - I had my first microneedling with Salmon DNA session at the clinic and it went really well. The staff were kind and explained everything clearly, which made me feel comfortable. The treatment was easier than I expected and the redness so far is mild!

    Looking forward to my next sessions.

  • Feb 2026

    I’ve had excellent experiences at Total Dermatology. The staff are always warm, friendly and thorough. I also appreciate how they consistently run on time. I highly recommend this practice to anyone looking for a skilled, kind and knowledgeable dermatology team.

  • Feb 2026

    The staff is incredibly kind, welcoming, and professional. The facility is very clean, modern, and well-maintained, which made me feel comfortable right away.

    Dr. Pilest is extremely knowledgeable and took the time to explain everything clearly while recommending the best approach for natural-looking results. The appointment process was smooth and efficient, and I’m very happy with my results. Highly recommend!

Hours

Monday: 9AM - 5:30PM
Tuesday: 9AM - 5:30PM
Wednesday: 9AM - 5:30PM
Thursday: 9AM - 5:30PM
Friday: 9AM - 5:30PM
Saturday: ClosedSunday: Closed

Tips

by appointment only wheelchair accessible accessible parking near entrance accepts credit cards quiet private lot parking free wi-fi gender-neutral restrooms bike parking

Location

16100 Sand Canyon Ave # 190, Irvine

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